Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH)

Microbial infections are a significant threat to public health, and resistance is on the rise, so new antibiotics with novel modes of action are urgently needed. The extracellular zinc metalloprotease collagenase H (ColH) from Clostridium histolyticum is a virulence factor that catalyses tissue dama...

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Detalles Bibliográficos
Autores principales: Voos, Katrin, Schönauer, Esther, Alhayek, Alaa, Haupenthal, Jörg, Andreas, Anastasia, Müller, Rolf, Hartmann, Rolf W., Brandstetter, Hans, Hirsch, Anna K. H., Ducho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251769/
https://www.ncbi.nlm.nih.gov/pubmed/33506625
http://dx.doi.org/10.1002/cmdc.202000994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251769/
https://www.ncbi.nlm.nih.gov/pubmed/33506625
http://dx.doi.org/10.1002/cmdc.202000994

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