STAT3/NF‐κB signalling disruption in M2 tumour‐associated macrophages is a major target of PLGA nanocarriers/PD‐L1 antibody immunomodulatory therapy in breast cancer

BACKGROUND AND PURPOSE: Inflammation associated with the tumour microenvironment (TME) is critical for cancer development, and immunotherapeutic strategies modulating the immune response in cancer have been crucial. In this study, a methotrexate‐loaded (MTX) poly(lactic‐co‐glycolic acid)‐based (PLGA...

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Detalles Bibliográficos
Autores principales: Cavalcante, Rômulo S., Ishikawa, Uta, Silva, Emanuell S., Silva‐Júnior, Arnóbio A., Araújo, Aurigena A., Cruz, Luis J., Chan, Alan B., de Araújo Júnior, Raimundo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251773/
https://www.ncbi.nlm.nih.gov/pubmed/33434950
http://dx.doi.org/10.1111/bph.15373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251773/
https://www.ncbi.nlm.nih.gov/pubmed/33434950
http://dx.doi.org/10.1111/bph.15373

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