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STAT3/NF‐κB signalling disruption in M2 tumour‐associated macrophages is a major target of PLGA nanocarriers/PD‐L1 antibody immunomodulatory therapy in breast cancer

BACKGROUND AND PURPOSE: Inflammation associated with the tumour microenvironment (TME) is critical for cancer development, and immunotherapeutic strategies modulating the immune response in cancer have been crucial. In this study, a methotrexate‐loaded (MTX) poly(lactic‐co‐glycolic acid)‐based (PLGA...

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Detalles Bibliográficos
Autores principales:	Cavalcante, Rômulo S., Ishikawa, Uta, Silva, Emanuell S., Silva‐Júnior, Arnóbio A., Araújo, Aurigena A., Cruz, Luis J., Chan, Alan B., de Araújo Júnior, Raimundo F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251773/ https://www.ncbi.nlm.nih.gov/pubmed/33434950 http://dx.doi.org/10.1111/bph.15373

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