CD5 levels define functionally heterogeneous populations of naïve human CD4(+) T cells

Studies in murine models show that subthreshold TCR interactions with self‐peptide are required for thymic development and peripheral survival of naïve T cells. Recently, differences in the strength of tonic TCR interactions with self‐peptide, as read‐out by cell surface levels of CD5, were associat...

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Detalles Bibliográficos
Autores principales: Sood, Aditi, Lebel, Marie‐Ève, Dong, Mengqi, Fournier, Marilaine, Vobecky, Suzanne J., Haddad, Élie, Delisle, Jean‐Sébastien, Mandl, Judith N., Vrisekoop, Nienke, Melichar, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Adaptive immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251777/
https://www.ncbi.nlm.nih.gov/pubmed/33682083
http://dx.doi.org/10.1002/eji.202048788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251777/
https://www.ncbi.nlm.nih.gov/pubmed/33682083
http://dx.doi.org/10.1002/eji.202048788

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