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VWF/ADAMTS13 Imbalance, But Not Global Coagulation or Fibrinolysis, Is Associated With Outcome and Bleeding in Acute Liver Failure

BACKGROUND AND AIMS: Recent studies of acute liver failure (ALF) in man and animals have suggested that rebalanced hemostasis occurs, with distinct hypercoagulable features clinically evidenced by a low risk of bleeding. Rodent models have shown a link between intrahepatic microthrombus formation an...

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Detalles Bibliográficos
Autores principales: Driever, Ellen G., Stravitz, R. Todd, Zhang, Jingwen, Adelmeijer, Jelle, Durkalski, Valerie, Lee, William M., Lisman, Ton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251778/
https://www.ncbi.nlm.nih.gov/pubmed/32767567
http://dx.doi.org/10.1002/hep.31507