Comprehensive Analysis of Binding Sites in Tubulin

Tubulin plays essential roles in vital cellular activities and is the target of a wide range of proteins and ligands. Here, using a combined computational and crystallographic fragment screening approach, we addressed the question of how many binding sites exist in tubulin. We identified 27 distinct...

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Detalles Bibliográficos
Autores principales: Mühlethaler, Tobias, Gioia, Dario, Prota, Andrea E., Sharpe, May E., Cavalli, Andrea, Steinmetz, Michel O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251789/
https://www.ncbi.nlm.nih.gov/pubmed/33951246
http://dx.doi.org/10.1002/anie.202100273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251789/
https://www.ncbi.nlm.nih.gov/pubmed/33951246
http://dx.doi.org/10.1002/anie.202100273

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