Biosynthesis of 6‐Hydroxymellein Requires a Collaborating Polyketide Synthase‐like Enzyme

The polyketide synthase (PKS)‐like protein TerB, consisting of inactive dehydratase, inactive C‐methyltransferase, and functional ketoreductase domains collaborates with the iterative non reducing PKS TerA to produce 6‐hydroxymellein, a key pathway intermediate during the biosynthesis of various fun...

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Detalles Bibliográficos
Autores principales: Kahlert, Lukas, Villanueva, Miranda, Cox, Russell J., Skellam, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251887/
https://www.ncbi.nlm.nih.gov/pubmed/33661567
http://dx.doi.org/10.1002/anie.202100969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251887/
https://www.ncbi.nlm.nih.gov/pubmed/33661567
http://dx.doi.org/10.1002/anie.202100969

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