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Germline sequence analysis of RABL3 in a large series of pancreatic ductal adenocarcinoma patients reveals no evidence of deleterious variants

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a 5‐year survival rate of less than 10%. Individuals with a pathogenic germline variant in a pancreatic cancer susceptibility gene are at an increased risk of developing pancreatic cancer. Understanding the inherited genetic basis of p...

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Detalles Bibliográficos
Autores principales: Roberts, Nicholas J., Grant, Robert C., Gallinger, Steven, Klein, Alison P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251898/
https://www.ncbi.nlm.nih.gov/pubmed/33724601
http://dx.doi.org/10.1002/gcc.22947