Imide Condensation as a Strategy for the Synthesis of Core‐Diversified G‐Quadruplex Ligands with Anticancer and Antiparasitic Activity

A facile imide coupling strategy for the one‐step preparation of G‐quadruplex ligands with varied core chemistries is described. The G‐quadruplex stabilization of a library of nine compounds was examined using FRET melting experiments, and CD, UV‐Vis, fluorescence and NMR titrations, identifying sev...

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Detalles Bibliográficos
Autores principales: Street, Steven T. G., Peñalver, Pablo, O'Hagan, Michael P., Hollingworth, Gregory J., Morales, Juan C., Galan, M. Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251916/
https://www.ncbi.nlm.nih.gov/pubmed/33780044
http://dx.doi.org/10.1002/chem.202100040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251916/
https://www.ncbi.nlm.nih.gov/pubmed/33780044
http://dx.doi.org/10.1002/chem.202100040

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