Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors

Withanolides constitute a well‐known family of plant‐based alkaloids characterised by widespread biological properties, including the ability of interfering with Hedgehog (Hh) signalling pathway. Following our interest in natural products and in anticancer compounds, we report here the synthesis of...

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Detalles Bibliográficos
Autores principales: Bonandi, Elisa, Mori, Mattia, Infante, Paola, Basili, Irene, Di Marcotullio, Lucia, Calcaterra, Andrea, Catti, Federica, Botta, Bruno, Passarella, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251939/
https://www.ncbi.nlm.nih.gov/pubmed/33811701
http://dx.doi.org/10.1002/chem.202100315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251939/
https://www.ncbi.nlm.nih.gov/pubmed/33811701
http://dx.doi.org/10.1002/chem.202100315

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