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Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors
Withanolides constitute a well‐known family of plant‐based alkaloids characterised by widespread biological properties, including the ability of interfering with Hedgehog (Hh) signalling pathway. Following our interest in natural products and in anticancer compounds, we report here the synthesis of...
Autores principales: | Bonandi, Elisa, Mori, Mattia, Infante, Paola, Basili, Irene, Di Marcotullio, Lucia, Calcaterra, Andrea, Catti, Federica, Botta, Bruno, Passarella, Daniele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251939/ https://www.ncbi.nlm.nih.gov/pubmed/33811701 http://dx.doi.org/10.1002/chem.202100315 |
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