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Absolute Quantification of Drug Vector Delivery to the Cytosol

Macromolecular drugs inefficiently cross membranes to reach their cytosolic targets. They require drug delivery vectors to facilitate their translocation across the plasma membrane or escape from endosomes. Optimization of these vectors has however been hindered by the difficulty to accurately measu...

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Detalles Bibliográficos
Autores principales: Lucchino, Marco, Billet, Anne, Bai, Siau‐Kun, Dransart, Estelle, Hadjerci, Justine, Schmidt, Frédéric, Wunder, Christian, Johannes, Ludger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252025/
https://www.ncbi.nlm.nih.gov/pubmed/33904231
http://dx.doi.org/10.1002/anie.202102332