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Absolute Quantification of Drug Vector Delivery to the Cytosol
Macromolecular drugs inefficiently cross membranes to reach their cytosolic targets. They require drug delivery vectors to facilitate their translocation across the plasma membrane or escape from endosomes. Optimization of these vectors has however been hindered by the difficulty to accurately measu...
Autores principales: | Lucchino, Marco, Billet, Anne, Bai, Siau‐Kun, Dransart, Estelle, Hadjerci, Justine, Schmidt, Frédéric, Wunder, Christian, Johannes, Ludger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252025/ https://www.ncbi.nlm.nih.gov/pubmed/33904231 http://dx.doi.org/10.1002/anie.202102332 |
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