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Altered Membrane Mechanics Provides a Receptor‐Independent Pathway for Serotonin Action

Serotonin, an important signaling molecule in humans, has an unexpectedly high lipid membrane affinity. The significance of this finding has evoked considerable speculation. Here we show that membrane binding by serotonin can directly modulate membrane properties and cellular function, providing an...

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Detalles Bibliográficos
Autores principales: Dey, Simli, Surendran, Dayana, Engberg, Oskar, Gupta, Ankur, Fanibunda, Sashaina E., Das, Anirban, Maity, Barun Kumar, Dey, Arpan, Visvakarma, Vicky, Kallianpur, Mamata, Scheidt, Holger A., Walker, Gilbert, Vaidya, Vidita A., Huster, Daniel, Maiti, Sudipta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252079/
https://www.ncbi.nlm.nih.gov/pubmed/33502812
http://dx.doi.org/10.1002/chem.202100328