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Activation of the Catalytic Activity of Thrombin for Fibrin Formation by Ultrasound

The regulation of enzyme activity is a method to control biological function. We report two systems enabling the ultrasound‐induced activation of thrombin, which is vital for secondary hemostasis. First, we designed polyaptamers, which can specifically bind to thrombin, inhibiting its catalytic acti...

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Detalles Bibliográficos
Autores principales: Zhao, Pengkun, Huo, Shuaidong, Fan, Jilin, Chen, Junlin, Kiessling, Fabian, Boersma, Arnold J., Göstl, Robert, Herrmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252103/
https://www.ncbi.nlm.nih.gov/pubmed/33939872
http://dx.doi.org/10.1002/anie.202105404