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Activation of the Catalytic Activity of Thrombin for Fibrin Formation by Ultrasound
The regulation of enzyme activity is a method to control biological function. We report two systems enabling the ultrasound‐induced activation of thrombin, which is vital for secondary hemostasis. First, we designed polyaptamers, which can specifically bind to thrombin, inhibiting its catalytic acti...
Autores principales: | Zhao, Pengkun, Huo, Shuaidong, Fan, Jilin, Chen, Junlin, Kiessling, Fabian, Boersma, Arnold J., Göstl, Robert, Herrmann, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252103/ https://www.ncbi.nlm.nih.gov/pubmed/33939872 http://dx.doi.org/10.1002/anie.202105404 |
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