Molecular characterisation of NPM1 and FLT3-ITD mutations in a central South African adult de novo acute myeloid leukaemia cohort

BACKGROUND: Recognition of molecular abnormalities in acute myeloid leukaemia (AML) has improved our understanding of its biology. NPM1 and FLT3-ITD mutations are recurrent in AML and clinically significant. NPM1 mutations are associated with a favourable prognosis, while FLT3-ITD mutations are an i...

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Detalles Bibliográficos
Autores principales: Kloppers, Jean F., de Kock, André, Cronjé, Johané, van Marle, Anne-Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252134/
https://www.ncbi.nlm.nih.gov/pubmed/34230878
http://dx.doi.org/10.4102/ajlm.v10i1.1363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252134/
https://www.ncbi.nlm.nih.gov/pubmed/34230878
http://dx.doi.org/10.4102/ajlm.v10i1.1363

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