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Quality Assurance of Commercial Insulin Formulations: Novel Assay Using Infrared Spectroscopy
BACKGROUND: For insulins in commercial formulations, degradation can be observed within the certified shelf life when not stored at recommended conditions. Elevated temperatures and exposure to shear forces can cause changes in the secondary structure of the hormone, leading to a decrease in pharmac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252148/ https://www.ncbi.nlm.nih.gov/pubmed/32281880 http://dx.doi.org/10.1177/1932296820913874 |