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PML-II regulates ERK and AKT signal activation and IFNα-induced cell death

BACKGROUND: The requirement of promyelocytic leukaemia protein (PML) in interferon (IFN)-induced cell apoptosis is well-established. However, the exact mechanisms by which the multiple isoforms of PML protein participate in this process remain not well-understood. We previously demonstrated that PML...

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Detalles Bibliográficos
Autores principales: Meng, Xueqiong, Chen, Yixiang, Macip, Salvador, Leppard, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252201/
https://www.ncbi.nlm.nih.gov/pubmed/34215258
http://dx.doi.org/10.1186/s12964-021-00756-5