Cargando…
PML-II regulates ERK and AKT signal activation and IFNα-induced cell death
BACKGROUND: The requirement of promyelocytic leukaemia protein (PML) in interferon (IFN)-induced cell apoptosis is well-established. However, the exact mechanisms by which the multiple isoforms of PML protein participate in this process remain not well-understood. We previously demonstrated that PML...
Autores principales: | Meng, Xueqiong, Chen, Yixiang, Macip, Salvador, Leppard, Keith |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252201/ https://www.ncbi.nlm.nih.gov/pubmed/34215258 http://dx.doi.org/10.1186/s12964-021-00756-5 |
Ejemplares similares
-
Promyelocytic Leukemia Protein Isoform II Promotes Transcription Factor Recruitment To Activate Interferon Beta and Interferon-Responsive Gene Expression
por: Chen, Yixiang, et al.
Publicado: (2015) -
Nuclear DNA helicase II is recruited to IFN-α–activated transcription sites at PML nuclear bodies
por: Fuchsová, Beata, et al.
Publicado: (2002) -
Regulation of NF-κB by PML and PML-RARα
por: Ahmed, Abrar, et al.
Publicado: (2017) -
poly(I:C) synergizes with proteasome inhibitors to induce apoptosis in cervical cancer cells
por: Meng, Xueqiong, et al.
Publicado: (2022) -
PML Degradation: Multiple Ways to Eliminate PML
por: Rabellino, Andrea, et al.
Publicado: (2013)