The energy sensor AMPK orchestrates metabolic and translational adaptation in expanding T helper cells

The importance of cellular metabolic adaptation in inducing robust T cell responses is well established. However, the mechanism by which T cells link information regarding nutrient supply to clonal expansion and effector function is still enigmatic. Herein, we report that the metabolic sensor adenos...

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Detalles Bibliográficos
Autores principales: Mayer, Katharina A., Smole, Ursula, Zhu, Ci, Derdak, Sophia, Minervina, Anastasia A., Salnikova, Maria, Witzeneder, Nadine, Christamentl, Anna, Boucheron, Nicole, Waidhofer‐Söllner, Petra, Trauner, Michael, Hoermann, Gregor, Schmetterer, Klaus G., Mamedov, Ilgar Z., Bilban, Martin, Ellmeier, Wilfried, Pickl, Winfried F., Gualdoni, Guido A., Zlabinger, Gerhard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252394/
https://www.ncbi.nlm.nih.gov/pubmed/33715236
http://dx.doi.org/10.1096/fj.202001763RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252394/
https://www.ncbi.nlm.nih.gov/pubmed/33715236
http://dx.doi.org/10.1096/fj.202001763RR

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