The Folding Landscapes of Human Telomeric RNA and DNA G‐Quadruplexes are Markedly Different

We investigated the folding kinetics of G‐quadruplex (G4) structures by comparing the K(+)‐induced folding of an RNA G4 derived from the human telomeric repeat‐containing RNA (TERRA25) with a sequence homologous DNA G4 (wtTel25) using CD spectroscopy and real‐time NMR spectroscopy. While DNA G4 fold...

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Detalles Bibliográficos
Autores principales: Müller, Diana, Bessi, Irene, Richter, Christian, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252441/
https://www.ncbi.nlm.nih.gov/pubmed/33539622
http://dx.doi.org/10.1002/anie.202100280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252441/
https://www.ncbi.nlm.nih.gov/pubmed/33539622
http://dx.doi.org/10.1002/anie.202100280

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