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Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin

Hypeptin is a cyclodepsipeptide antibiotic produced by Lysobacter sp. K5869, isolated from an environmental sample by the iChip technology, dedicated to the cultivation of previously uncultured microorganisms. Hypeptin shares structural features with teixobactin and exhibits potent activity against...

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Detalles Bibliográficos
Autores principales: Wirtz, Daniel A., Ludwig, Kevin C., Arts, Melina, Marx, Carina E., Krannich, Sebastian, Barac, Paul, Kehraus, Stefan, Josten, Michaele, Henrichfreise, Beate, Müller, Anna, König, Gabriele M., Peoples, Aaron J., Nitti, Anthony, Spoering, Amy L., Ling, Losee L., Lewis, Kim, Crüsemann, Max, Schneider, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252469/
https://www.ncbi.nlm.nih.gov/pubmed/33768646
http://dx.doi.org/10.1002/anie.202102224