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Less Unfavorable Salt Bridges on the Enzyme Surface Result in More Organic Cosolvent Resistance
Biocatalysis for the synthesis of fine chemicals is highly attractive but usually requires organic (co‐)solvents (OSs). However, native enzymes often have low activity and resistance in OSs and at elevated temperatures. Herein, we report a smart salt bridge design strategy for simultaneously improvi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252522/ https://www.ncbi.nlm.nih.gov/pubmed/33687787 http://dx.doi.org/10.1002/anie.202101642 |