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Results of a randomized phase III/IV trial comparing intermittent bolus versus continuous infusion of antihaemophilic factor (recombinant) in adults with severe or moderately severe haemophilia A undergoing major orthopaedic surgery

INTRODUCTION: In patients with haemophilia A undergoing surgery, factor VIII (FVIII) replacement therapy by continuous infusion (CI) may offer an alternative to bolus infusion (BI). AIM: To compare the perioperative haemostatic efficacy and safety of antihaemophilic factor (recombinant) (ADVATE(®);...

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Detalles Bibliográficos
Autores principales: Pabinger, Ingrid, Mamonov, Vasily, Windyga, Jerzy, Engl, Werner, Doralt, Jennifer, Tangada, Srilatha, Spotts, Gerald, Ewenstein, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252548/
https://www.ncbi.nlm.nih.gov/pubmed/33772963
http://dx.doi.org/10.1111/hae.14219