E. coli Nickel‐Iron Hydrogenase 1 Catalyses Non‐native Reduction of Flavins: Demonstration for Alkene Hydrogenation by Old Yellow Enzyme Ene‐reductases

A new activity for the [NiFe] uptake hydrogenase 1 of Escherichia coli (Hyd1) is presented. Direct reduction of biological flavin cofactors FMN and FAD is achieved using H(2) as a simple, completely atom‐economical reductant. The robust nature of Hyd1 is exploited for flavin reduction across a broad...

Descripción completa

Detalles Bibliográficos
Autores principales: Joseph Srinivasan, Shiny, Cleary, Sarah E., Ramirez, Miguel A., Reeve, Holly A., Paul, Caroline E., Vincent, Kylie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252551/
https://www.ncbi.nlm.nih.gov/pubmed/33721401
http://dx.doi.org/10.1002/anie.202101186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252551/
https://www.ncbi.nlm.nih.gov/pubmed/33721401
http://dx.doi.org/10.1002/anie.202101186

Ejemplares similares