Cell‐Based Identification of New IDO1 Modulator Chemotypes

The immunoregulatory enzyme indoleamine‐2,3‐dioxygenase (IDO1) strengthens cancer immune escape, and inhibition of IDO1 by means of new chemotypes and mechanisms of action is considered a promising opportunity for IDO1 inhibitor discovery. IDO1 is a cofactor‐binding, redox‐sensitive protein, which c...

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Detalles Bibliográficos
Autores principales: Hennes, Elisabeth, Lampe, Philipp, Dötsch, Lara, Bruning, Nora, Pulvermacher, Lisa‐Marie, Sievers, Sonja, Ziegler, Slava, Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252559/
https://www.ncbi.nlm.nih.gov/pubmed/33565680
http://dx.doi.org/10.1002/anie.202016004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252559/
https://www.ncbi.nlm.nih.gov/pubmed/33565680
http://dx.doi.org/10.1002/anie.202016004

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