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Post‐translational regulation of PGC‐1α modulates fibrotic repair

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease associated with mitochondrial oxidative stress. Mitochondrial reactive oxygen species (mtROS) are important for cell homeostasis by regulating mitochondrial dynamics. Here, we show that IPF BAL cells exhibited increased mitochondrial...

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Detalles Bibliográficos
Autores principales: Larson‐Casey, Jennifer L., Gu, Linlin, Davis, Dana, Cai, Guo‐Qiang, Ding, Qiang, He, Chao, Carter, A. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252570/
https://www.ncbi.nlm.nih.gov/pubmed/34038004
http://dx.doi.org/10.1096/fj.202100339R