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Pyrimidin‐6‐yl Trifluoroborate Salts as Versatile Templates for Heterocycle Synthesis

We report a novel and general method to access a highly under‐studied privileged scaffold—pyrimidines bearing a trifluoroborate at C4, and highlight the broad utility of these intermediates in a rich array of downstream functionalization reactions. This chemistry is underpinned by the unique feature...

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Detalles Bibliográficos
Autores principales: Cousins, David L., Fricero, Prisca, Kopf, Kenji P. M., McColl, Elliot J., Czechtizky, Werngard, Lim, Yee Hwee, Harrity, Joseph P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252621/
https://www.ncbi.nlm.nih.gov/pubmed/33570831
http://dx.doi.org/10.1002/anie.202101297