Direct Catalytic N‐Alkylation of α‐Amino Acid Esters and Amides Using Alcohols with High Retention of Stereochemistry

The direct functionalization of naturally abundant chiral scaffolds such as α‐amino acid esters or amides with widely abundant alcohols, without any racemization, is a demanding transformation that is of central importance for the synthesis of bio‐active compounds. Herein a robust and general method...

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Detalles Bibliográficos
Autores principales: Yan, Tao, Feringa, Ben L., Barta, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252633/
https://www.ncbi.nlm.nih.gov/pubmed/33961350
http://dx.doi.org/10.1002/cssc.202100373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252633/
https://www.ncbi.nlm.nih.gov/pubmed/33961350
http://dx.doi.org/10.1002/cssc.202100373

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