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5‐Hydroxymethyl‐, 5‐Formyl‐ and 5‐Carboxydeoxycytidines as Oxidative Lesions and Epigenetic Marks

The four non‐canonical nucleotides in the human genome 5‐methyl‐, 5‐hydroxymethyl‐, 5‐formyl‐ and 5‐carboxydeoxycytidine (mdC, hmdC, fdC and cadC) form a second layer of epigenetic information that contributes to the regulation of gene expression. Formation of the oxidized nucleotides hmdC, fdC and...

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Detalles Bibliográficos
Autores principales: Schelter, Florian, Kirchner, Angie, Traube, Franziska R., Müller, Markus, Steglich, Wolfgang, Carell, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252671/
https://www.ncbi.nlm.nih.gov/pubmed/33769637
http://dx.doi.org/10.1002/chem.202100551