Ibuprofen enantiomers in premature neonates with patent ductus arteriosus: Preliminary data on an unexpected pharmacokinetic profile of S(+)‐ibuprofen

S(+)‐ibuprofen (S‐IBU) and R(−)‐ibuprofen (R‐IBU) concentrations were measured in 16 neonates with patent ductus arteriosus during a cycle of therapy (three intravenous doses of 10–5–5 mg kg(−1) at 24‐h intervals), at the end of the first infusion and 6, 24, 48, and 72 h later. Data were analyzed wi...

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Detalles Bibliográficos
Autores principales: Padrini, Roberto, Ancora, Caterina, Nardo, Daniel, De Rosa, Giovanni, Salvadori, Sabrina, Bonadies, Luca, Frigo, Anna Chiara, Lago, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252714/
https://www.ncbi.nlm.nih.gov/pubmed/33779002
http://dx.doi.org/10.1002/chir.23308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252714/
https://www.ncbi.nlm.nih.gov/pubmed/33779002
http://dx.doi.org/10.1002/chir.23308

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