Apical CLC‐2 in retinal pigment epithelium is crucial for survival of the outer retina

Knockout of the chloride channel protein 2 (CLC‐2; CLCN2) results in fast progressing blindness in mice. Retinal Pigment Epithelium (RPE) and photoreceptors undergo, in parallel, rapid, and profound morphological changes and degeneration. Immunohistochemistry and electron microscopy of the outer ret...

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Detalles Bibliográficos
Autores principales: Hanke‐Gogokhia, Christin, Lehmann, Guillermo L., Benedicto, Ignacio, de la Fuente‐Ortega, Erwin, Arshavsky, Vadim Y., Schreiner, Ryan, Rodriguez‐Boulan, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252757/
https://www.ncbi.nlm.nih.gov/pubmed/34085737
http://dx.doi.org/10.1096/fj.202100349R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252757/
https://www.ncbi.nlm.nih.gov/pubmed/34085737
http://dx.doi.org/10.1096/fj.202100349R

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