Factor VIII activity and bleeding risk during prophylaxis for severe hemophilia A: a population pharmacokinetic model

During factor VIII prophylaxis for severe hemophilia A, bleeding risk increases with time when factor VIII activity is below 1%. However, maintaining trough activity above 1% does not protect all patients from bleeding. The relationship between factor VIII activity during prophylaxis and bleeding ri...

Descripción completa

Detalles Bibliográficos
Autores principales: Tiede, Andreas, Karim, Faraizah Abdul, Jiménez-Yuste, Victor, Klamroth, Robert, Lejniece, Sandra, Suzuki, Takashi, Groth, Andreas, Santagostino, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252934/
https://www.ncbi.nlm.nih.gov/pubmed/32327501
http://dx.doi.org/10.3324/haematol.2019.241554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252934/
https://www.ncbi.nlm.nih.gov/pubmed/32327501
http://dx.doi.org/10.3324/haematol.2019.241554

Ejemplares similares