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Factor VIII activity and bleeding risk during prophylaxis for severe hemophilia A: a population pharmacokinetic model
During factor VIII prophylaxis for severe hemophilia A, bleeding risk increases with time when factor VIII activity is below 1%. However, maintaining trough activity above 1% does not protect all patients from bleeding. The relationship between factor VIII activity during prophylaxis and bleeding ri...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Fondazione Ferrata Storti
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252934/ https://www.ncbi.nlm.nih.gov/pubmed/32327501 http://dx.doi.org/10.3324/haematol.2019.241554 |