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Crucial role of hematopoietic JAK2 V617F in the development of aortic aneurysms

JAK2 V617F is the most frequent driver mutation in myeloproliferative neoplasms (MPN) and is associated with vascular complications. However, the impact of hematopoietic JAK2 V617F on aortic aneurysms (AA) remains unknown. Our cross-sectional study indicated that nine (23%) of 39 MPN patients with J...

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Detalles Bibliográficos
Autores principales: Yokokawa, Tetsuro, Misaka, Tomofumi, Kimishima, Yusuke, Wada, Kento, Minakawa, Keiji, Sugimoto, Koichi, Ishida, Takafumi, Morishita, Soji, Komatsu, Norio, Ikeda, Kazuhiko, Takeishi, Yasuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252954/
https://www.ncbi.nlm.nih.gov/pubmed/33567809
http://dx.doi.org/10.3324/haematol.2020.264085