CDH6‐activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers

Cadherin 6 (CDH6) is significantly overexpressed in advanced ovarian and renal cancers. However, the role of CDH6 in cancer metastasis is largely unclear. Here, we investigated the impact of CDH6 expression on integrin‐mediated metastatic progression. CDH6 preferentially bound to αIIbβ3 integrin, a...

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Detalles Bibliográficos
Autores principales: Bartolomé, Rubén A., Robles, Javier, Martin‐Regalado, Ángela, Pintado‐Berninches, Laura, Burdiel, Miranda, Jaén, Marta, Aizpurúa, Carmen, Imbaud, Juan I., Casal, José Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253092/
https://www.ncbi.nlm.nih.gov/pubmed/33715292
http://dx.doi.org/10.1002/1878-0261.12947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253092/
https://www.ncbi.nlm.nih.gov/pubmed/33715292
http://dx.doi.org/10.1002/1878-0261.12947

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