Reduced WNT5A signaling in melanoma cells favors an amoeboid mode of invasion

Tumor cells invade and spread via either a mesenchymal or an amoeboid mode of migration. Amoeboid tumor cells have a rounded morphology and pronounced RhoA activity. Here, we investigate how WNT5A signaling, a tumor promotor in melanoma, relates to Rho GTPase activity and amoeboid migration. We comp...

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Detalles Bibliográficos
Autores principales: Jobe, Njainday Pulo, Åsberg, Lisa, Andersson, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253101/
https://www.ncbi.nlm.nih.gov/pubmed/33969605
http://dx.doi.org/10.1002/1878-0261.12974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253101/
https://www.ncbi.nlm.nih.gov/pubmed/33969605
http://dx.doi.org/10.1002/1878-0261.12974

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