Cell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer

To conquer the drug resistance of tumors and the poor solubility of paclitaxel (PTX), two PTX-cell-penetrating peptide conjugates (PTX-CPPs), PTX-TAT and PTX-LMWP, were synthesized and evaluated for the first time. Compared with free PTX, PTX-CPPs displayed significantly enhanced cellular uptake, el...

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Detalles Bibliográficos
Autores principales: Duan, Ziqing, Chen, Cuitian, Qin, Jing, Liu, Qi, Wang, Qi, Xu, Xinchun, Wang, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253140/
https://www.ncbi.nlm.nih.gov/pubmed/28468542
http://dx.doi.org/10.1080/10717544.2017.1321060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253140/
https://www.ncbi.nlm.nih.gov/pubmed/28468542
http://dx.doi.org/10.1080/10717544.2017.1321060

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