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Combined inhibition of STAT and Notch signalling effectively suppresses tumourigenesis by inducing apoptosis and inhibiting proliferation, migration and invasion in glioblastoma cells

Glioblastoma multiforme (GBM) is the most aggressive primary brain cancer and this is due to cancer cells being apoptosis-resistant and having increased cell proliferation, migration, invasion, and angiogenesis properties. Previous studies have indicated both STAT and Notch pathways being important...

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Detalles Bibliográficos
Autores principales: Tulip, Israt Jahan, Kim, Sung-Ok, Kim, Eun-Jung, Kim, Jaebong, Lee, Jae Yong, Kim, Hyunggee, Kim, Sung-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253205/
https://www.ncbi.nlm.nih.gov/pubmed/34262659
http://dx.doi.org/10.1080/19768354.2021.1942983