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Combining Metagenomic Sequencing With Whole Exome Sequencing to Optimize Clinical Strategies in Neonates With a Suspected Central Nervous System Infection

OBJECTIVES: Central nervous system (CNS) infection has a high incidence and mortality in neonates, but conventional tests are time-consuming and have a low sensitivity. Some rare genetic diseases may have some similar clinical manifestations as CNS infection. Therefore, we aimed to evaluate the perf...

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Detalles Bibliográficos
Autores principales: Ge, Mengmeng, Gan, Mingyu, Yan, Kai, Xiao, Feifan, Yang, Lin, Wu, Bingbing, Xiao, Mili, Ba, Yin, Zhang, Rong, Wang, Jin, Cheng, Guoqiang, Wang, Laishuan, Cao, Yun, Zhou, Wenhao, Hu, Liyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253254/
https://www.ncbi.nlm.nih.gov/pubmed/34222042
http://dx.doi.org/10.3389/fcimb.2021.671109