PP1 regulatory subunit NIPP1 regulates transcription of E2F1 target genes following DNA damage

DNA damage induces transcriptional repression of E2F1 target genes and a reduction in histone H3‐Thr(11) phosphorylation (H3‐pThr(11)) at E2F1 target gene promoters. Dephosphorylation of H3‐pThr11 is partly mediated by Chk1 kinase and protein phosphatase 1γ (PP1γ) phosphatase. Here, we isolated NIPP...

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Detalles Bibliográficos
Autores principales: Hanaki, Shunsuke, Habara, Makoto, Masaki, Takahiro, Maeda, Keisuke, Sato, Yuki, Nakanishi, Makoto, Shimada, Midori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253265/
https://www.ncbi.nlm.nih.gov/pubmed/33939241
http://dx.doi.org/10.1111/cas.14924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253265/
https://www.ncbi.nlm.nih.gov/pubmed/33939241
http://dx.doi.org/10.1111/cas.14924

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