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PP1 regulatory subunit NIPP1 regulates transcription of E2F1 target genes following DNA damage
DNA damage induces transcriptional repression of E2F1 target genes and a reduction in histone H3‐Thr(11) phosphorylation (H3‐pThr(11)) at E2F1 target gene promoters. Dephosphorylation of H3‐pThr11 is partly mediated by Chk1 kinase and protein phosphatase 1γ (PP1γ) phosphatase. Here, we isolated NIPP...
Autores principales: | Hanaki, Shunsuke, Habara, Makoto, Masaki, Takahiro, Maeda, Keisuke, Sato, Yuki, Nakanishi, Makoto, Shimada, Midori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253265/ https://www.ncbi.nlm.nih.gov/pubmed/33939241 http://dx.doi.org/10.1111/cas.14924 |
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