A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy

Recent studies have revealed that tumor cells decrease their immunogenicity by epigenetically repressing the expression of highly immunogenic antigens to survive in immunocompetent hosts. We hypothesized that these epigenetically hidden “stealth” antigens should be favorable targets for cancer immun...

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Detalles Bibliográficos
Autores principales: Kosaka, Akemi, Yajima, Yuki, Hatayama, Mayumi, Ikuta, Katsuya, Sasaki, Takaaki, Hirai, Noriko, Yasuda, Syunsuke, Nagata, Marino, Hayashi, Ryusuke, Harabuchi, Shohei, Ohara, Kenzo, Ohara, Mizuho, Kumai, Takumi, Ishibashi, Kei, Hirata‐Nozaki, Yui, Nagato, Toshihiro, Oikawa, Kensuke, Harabuchi, Yasuaki, Celis, Esteban, Okumura, Toshikatsu, Ohsaki, Yoshinobu, Kobayashi, Hiroya, Ohkuri, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253266/
https://www.ncbi.nlm.nih.gov/pubmed/34009705
http://dx.doi.org/10.1111/cas.14973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253266/
https://www.ncbi.nlm.nih.gov/pubmed/34009705
http://dx.doi.org/10.1111/cas.14973

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