NAD(P)HX epimerase downregulation promotes tumor progression through ROS/HIF‐1α signaling in hepatocellular carcinoma

Reactive oxygen species (ROS) derived from aberrant tumor metabolism could contribute to tumor invasion and metastasis. NAD(P)HX Epimerase (NAXE), an epimerase that allows the repair of damaged forms of antioxidant NADPH, is a potential cellular ROS scavenger and its role in tumor development is sti...

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Detalles Bibliográficos
Autores principales: Sun, Bo, Yu, Lei, Xu, Cong, Li, Yi‐Ming, Zhao, Yan‐Rong, Cao, Mo‐Mo, Yang, Lian‐Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253267/
https://www.ncbi.nlm.nih.gov/pubmed/33932069
http://dx.doi.org/10.1111/cas.14925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253267/
https://www.ncbi.nlm.nih.gov/pubmed/33932069
http://dx.doi.org/10.1111/cas.14925

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