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NAD(P)HX epimerase downregulation promotes tumor progression through ROS/HIF‐1α signaling in hepatocellular carcinoma
Reactive oxygen species (ROS) derived from aberrant tumor metabolism could contribute to tumor invasion and metastasis. NAD(P)HX Epimerase (NAXE), an epimerase that allows the repair of damaged forms of antioxidant NADPH, is a potential cellular ROS scavenger and its role in tumor development is sti...
Autores principales: | Sun, Bo, Yu, Lei, Xu, Cong, Li, Yi‐Ming, Zhao, Yan‐Rong, Cao, Mo‐Mo, Yang, Lian‐Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253267/ https://www.ncbi.nlm.nih.gov/pubmed/33932069 http://dx.doi.org/10.1111/cas.14925 |
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