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RAG enhances BCR‐ABL1‐positive leukemic cell growth through its endonuclease activity in vitro and in vivo
BCR‐ABL1 gene fusion associated with additional DNA lesions involves the pathogenesis of chronic myelogenous leukemia (CML) from a chronic phase (CP) to a blast crisis of B lymphoid (CML‐LBC) lineage and BCR‐ABL1 (+) acute lymphoblastic leukemia (BCR‐ABL1 (+) ALL). The recombination‐activating gene...
Autores principales: | Yuan, Meng, Wang, Yang, Qin, Mengting, Zhao, Xiaohui, Chen, Xiaodong, Li, Dandan, Miao, Yinsha, Otieno Odhiambo, Wood, Liu, Huasheng, Ma, Yunfeng, Ji, Yanhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253288/ https://www.ncbi.nlm.nih.gov/pubmed/33949040 http://dx.doi.org/10.1111/cas.14939 |
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