Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells

[Image: see text] Gene expression regulation by small interfering RNA (siRNA) holds promise in treating a wide range of diseases through selective gene silencing. However, successful clinical application of nucleic acid-based therapy requires novel delivery options. Herein, to achieve efficient deli...

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Detalles Bibliográficos
Autores principales: Pediconi, Natalia, Ghirga, Francesca, Del Plato, Cristina, Peruzzi, Giovanna, Athanassopoulos, Constantinos M., Mori, Mattia, Crestoni, Maria Elisa, Corinti, Davide, Ugozzoli, Franco, Massera, Chiara, Arcovito, Alessandro, Botta, Bruno, Boffi, Alberto, Quaglio, Deborah, Baiocco, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253483/
https://www.ncbi.nlm.nih.gov/pubmed/33978420
http://dx.doi.org/10.1021/acs.bioconjchem.1c00137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253483/
https://www.ncbi.nlm.nih.gov/pubmed/33978420
http://dx.doi.org/10.1021/acs.bioconjchem.1c00137

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