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Effects of donepezil on the amplitude of low-frequency fluctuations in the brain of patients with Alzheimer’s disease: evidence from resting-state functional magnetic resonance imaging

OBJECTIVES: To monitor the effects of donepezil on spontaneous neuronal activity (SNA), and the mechanisms underlying these effects in patients with mild-to-moderate Alzheimer’s disease, using the amplitude of low-frequency fluctuations (ALFFs), a metric of resting-state functional MRI (rs-fMRI). ME...

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Detalles Bibliográficos
Autores principales: Yang, Hua, Zhang, Jiangtao, Cheng, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253505/
https://www.ncbi.nlm.nih.gov/pubmed/34029287
http://dx.doi.org/10.1097/WNR.0000000000001659