Analysis of gene expression and mutation data points on contribution of transcription to the mutagenesis by APOBEC enzymes

Since the discovery of the role of the APOBEC enzymes in human cancers, the mechanisms of this type of mutagenesis remain little understood. Theoretically, targeting of single-stranded DNA by the APOBEC enzymes could occur during cellular processes leading to the unwinding of DNA double-stranded str...

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Detalles Bibliográficos
Autores principales: Chervova, Almira, Fatykhov, Bulat, Koblov, Alexander, Shvarov, Evgeny, Preobrazhenskaya, Julia, Vinogradov, Dmitry, Ponomarev, Gennady V, Gelfand, Mikhail S, Kazanov, Marat D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Cancer Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253550/
https://www.ncbi.nlm.nih.gov/pubmed/34316712
http://dx.doi.org/10.1093/narcan/zcab025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253550/
https://www.ncbi.nlm.nih.gov/pubmed/34316712
http://dx.doi.org/10.1093/narcan/zcab025

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